INVESTIGASI SIFAT MEKANIK MODEL BIODEGRADABLE STENT BERBASIS BAHAN PLLA
Abstrak
Penyakit kardiovaskular merupakan penyebab kematian tertinggi di dunia, dengan penyakit terkait penyempitan pembuluh darah menjadi penyebab utama kematian di Indonesia. Salah satu solusi untuk menangani penyempitan pembuluh darah adalah penggunaan stent, salah satunya adalah biodegradable polymer stent yang terbuat dari poly L-lactic acid (PLLA). Stent yang diteliti dalam penelitian ini memiliki desain batik (BT) dengan strut searah (S><), kombinasi struktur open cell dan close cell. Penelitian ini menggunakan metode analisis desain dengan bantuan perangkat lunak Abaqus student melalui finite element method (FEM). Data dikumpulkan dengan mensimulasikan pemberian momen pada setiap kombinasi desain stent pada konfigurasi crimped dan expanded, dengan variasi ketebalan stent yaitu 120 µm, 130 µm, dan 140 µm. Hasil penelitian menunjukkan bahwa pada konfigurasi crimped, stent dengan ketebalan 130 µm menghasilkan nilai curvature index tertinggi, yang menunjukkan fleksibilitas terbaik. Sementara itu, pada konfigurasi expanded, stent dengan ketebalan 120 µm memberikan hasil terbaik untuk fleksibilitas. Penelitian ini berkontribusi signifikan terhadap pengembangan stent biodegradabel yang lebih fleksibel dan optimal, dengan implikasi praktis dalam meningkatkan desain stent untuk mengurangi komplikasi pasca-implantasi dan meningkatkan hasil klinis bagi pasien dengan penyakit kardiovaskular.
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